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filingDate 2001-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_318f4ae66e054d5b49494a995b325fdc
publicationDate 2001-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0178880-A1
titleOfInvention Method of reducing ion fragmentation in mass spectrometry
abstract A method for the reducing ion fragmentation in mass spectrometry analysis is described. A sample and a carrier gas are expanded to form a molecular beam of sample molecules having the carrier gas adsorbed, or condensed, thereon. Ionization of the sample is accompanied by rapid evaporation of the adsorbed carrier gas, which cools the ions and effictively reduces ion fragmentation. An apparatus for mass spectrometry analysis according to the subject methods is provided. By using the method of the invention and reducing ion fragmentation it is possible to carry out mass spectrometry on molecules such as DNA sequences which could not ordinarily be so analyzed.
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priorityDate 2000-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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