| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_086c777a88d48fb03acd8e61ed72611c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_db3be89de48adb30132f44f1e098c7cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bf13596c2f45c98d02044fcb0e0e5517
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_96472ed51f7a84ad5d65a0b10a69f68c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c8cbbf2290b3f3a9988da29598baa2c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-554
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0061
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K-
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 |
| filingDate |
2001-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dd23fd7172b60102908a7bc9ebba78a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_11b37a52ed5773cd2c868fccaa337da5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2c2830d77d6f708c713618519f4fe35
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1b9e1099320bae7e8dc3b6869396f41 |
| publicationDate |
2001-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0176531-A2 |
| titleOfInvention |
Bile acid containing prodrugs with enhanced bioavailability |
| abstract |
Many compounds have poor bioavailability or variable bioavailability because of poor absorption of the compound in the small intestine. Conjugation of the compound with bile acid to form a prodrug will increase the bioavailibility of the compound and/or reduce the bioavailability variability of the compound because of the active transport of the prodrug by the intestinal bile acid transporter and because of increased lipophilic nature of the prodrug. A linker group can be used between the bile acid and the compound. One example of a bile acid containing prodrug is acyclovir valylchenodeoxycholate, where valine is the linker group. Another example of this prodrug is atenolol cholic acid amide. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1343805-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10350169-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7989417-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1343805-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1358200-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7678782-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7598235-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7144877-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6984634-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009530399-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1358200-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006513247-A |
| priorityDate |
2000-04-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |