http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0173122-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5c06d224399ac930f5e1ce1cdd16068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_04129afaea6a19d29dbeacbc44051583 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00eda22524f7a596f29780d882ea956f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5cf374ecaed27c8b9bd75d56acd7e801 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bfcc591d140a65b691d049c47d415f8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_99d5a1f03c280a68b1a17ea3149fa7e5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6837 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6837 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2000-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd98a9152638efacb8ea20dc34aaadb1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79b33c2fa2ffcc363831937e1a9fa6ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a5d476686e01dc5a3f628bd24a3b5bbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8151287489aeca21d148decb617f9178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7e6c0db4b202b2a84220ee68bc56bdb |
| publicationDate | 2001-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0173122-A1 |
| titleOfInvention | Methods for determination of single nucleic acid polymorphisms using a bioelectronic microchip |
| abstract | Methods are provided for the analysis and determination of the nature of single nucleic acid polymorphisms (SNPs) in a genetic target. In one method of this invention, the nature of the SNPs in the genetic target is determined by the steps of providing a plurality of hybridization complexes arrayed on a plurality of test sites on an electronically bioactive microchip, where the hybridization complex includes at least a nucleic acid target containing a SNP, a stabilizer probe having a sequence complementary to the target sequence and/or reporter probe, and a reporter probe having a selected sequence complementary to either the stabilizer or the same target sequence strand wherein a selected sequence of the reporter includes either a wild type nucleotide or a nucleotide corresponding to the SNP of the target. In accordance with the invention, the stabilizer, reporter and target amplicons are hybridized using electronic assistance of the microchip system such that base-stacking energies are utilized in discerning among other identifying indicators, the presence of wild type or polymorphism sequence. Applications include disease diagnostics, such as for the identification of polymorphisms in structural genes, regulatory regions, antibiotic or chemotherapeutic resistance conferring regions, or for SNPs associated with speciation or used for determination of genetic linkage. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004044242-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107075565-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107075565-A |
| priorityDate | 2000-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.