| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c75b3ac6a08127c7618c48ee3bd0cdb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1b0c198757da18cf77dfbdcef00abb70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c5e00bff6cb15ffafd60d7bc82b817f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2299-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 |
| filingDate |
2001-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d7c959060abe3a1e6b6ddd7173010a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0aec72c4092dc7dd494d8da6ff817154 |
| publicationDate |
2001-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0172823-A1 |
| titleOfInvention |
Crystal structure of the (aml1 runt domain) / (cbfbeta) heterodimer and the ternary complex with dna |
| abstract |
The present invention relates to a crystal comprising the AML1 Runt domain and/or CBFβ. The invention also relates to a structural model of the AML1 Runt domain and/or CBFβ, and of the interaction of the AML1 Runt domain with DNA, and an improved means for the design of ligands which are capable of binding the AML1 Runt domain and/or CBFβ and/or modulating the DNA-binding capacity of the AML1 Runt domain. |
| priorityDate |
2000-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |