http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0166096-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6671579631a085f58f4bf2a228922374 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5c648214f5da8a4ea81c6de8641014f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dc55ec28f151753222c236f456a6680d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4409 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-662 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-185 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4409 |
| filingDate | 2001-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12ae83751e0fd85082dfb3f76fe877b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9ab61e5f68d34b811e32c13e8aeccad |
| publicationDate | 2001-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0166096-A3 |
| titleOfInvention | Compositions for prevention and treatment of dementia |
| abstract | 4,4'-diaminodiphenylsulphone is a bactericide and anti-inflammatory agent. It is known to have therapeutic activity against leprosy, dermatitis herpetiformis, actinomycotic mycetoma, asthma, malaria, rheumatoid arthritis, Kaposiís sarcoma, pneumocystis carinii (pneumonia), subcorneal pustular dermatosis and cystic acne, in patients in need of such therapy. It is also known to have therapeutic activity against memory loss in patients in need of such therapy, including patients suffering from Alzheimer disease and related neurodegenerative disorders. Donepezil hydrochloride (donepezil) is an acetylcholinesterase inhibitor that is currently used for the symptomatic treatment of Alzheimer disease in patients in need of such therapy. It has now been found that combinations of 4,4'-diaminodiphenylsulphone and cholinesterase inhibitors unexpectedly show synergistic effects in the prevention and/or treatment of dementia. The present invention relates to novel compositions and methods of preventing and/or treating dementia using combinations of 4,4'-diaminodiphenylsulphone and a cholinesterase inhibitor (preferably donepezil). The method involves the administration to such individuals a drug composition of 4,4'-diaminodiphenylsulphone and a cholinesterase inhibitor. The invention also relates to a method of preventing and/or treating dementia including senile dementia, that involves the use of this combination of drugs. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8859628-B2 |
| priorityDate | 2000-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.