| abstract |
A device (10) for the transport of fluids through a biological barrier includes a number of microneedles (16) projecting from the front face (14) of a substrate (12). A conduit (18) is associated with each of the microneedles (16) to provide a flow path for transport of fluid through a hole in the biological barrier formed by the corresponding microneedle (16). Each of the microneedles (16) is configured to provide a penetrating tip (20), and each conduit (18) terminates at an opening (22) which is proximal with respect to the microneedle tip (20). Also described are microneedle-based devices with integrated MEMS pumping configurations for withdrawal and/or delivery of fluids, and remote healthcare systems based on such devices. |