http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0160985-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ecb7c6f6c9e964e4d605a21410eb017d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8af5c11fe2664d15ac3879b1062fd965 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_68c213ba9952360f439567152e047b18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d7fbf2e40f47e22455b27b21d3bdd6c7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1077 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
| filingDate | 2001-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_653a9934a46751c99b131ddda07e67a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ac02fa01dc5f078e7cec4db90463f3c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf28e2d468190c89c1c160af4a4b989f |
| publicationDate | 2002-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0160985-A3 |
| titleOfInvention | Compositions, methods and kits relating to uridine phosphorylase gene mutations |
| abstract | The present invention relates to human uridine phosphorylase nucleic acids and proteins encoded thereby. More specifically, the invention discloses that uridine phosphorylase in certain tumor tissues is resistant to inhibition by uridine phosphorylase inhibitor (UPI). The invention further relates to identification of mutations associated with uridine phosphorylase resistance to UPIs. These mutations include mutations located in exon 1 and exon 6. More specifically, the mutations include, but are not limited to, a change from a C to T at nucleotide 40, a C to T at nucleotide 135, a C to G at nucleotide 178, an A to C at nucleotide 182, a C to T at nucleotide 186, a G to A at nucleotide 713, and a G to A at nucleotide 752. The invention also relates to methods and kits relating to the nucleic and amino encoding UPase resistant to UPIs and uses therefor. |
| priorityDate | 2000-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.