Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6d412b5b17a66bd97b20e3dca2c38db1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9bf7439808d578ab8c3698f7560fe4ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e80bec33c217963fde7b61eb2ef2f3e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ba19918947e7271d4f06669d4e48b48 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2830-002 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0058 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate |
2001-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8243c54d2e6bed70bd2ddda860cc8f9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5a55298ec440afcf487df6cb79bc47a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d32d46801e6bd79d9ecd4770691c7faa |
publicationDate |
2001-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0160413-A2 |
titleOfInvention |
Recombinant vector expressing a beta2-adrenergic receptor and use in treating airway and vascular diseases |
abstract |
A method of treating a human having airway or vascular disease comprises administering to at least one cell type selected from airway epithelial cells, airway smooth muscle cells, blood vessel endothelial cells, and blood vessel smooth muscle cells, a first composition comprising a vector comprising a DNA sequence encoding a β2AR (β2-adrenergic receptor) or a mutant thereof, operably linked to a promoter that is functional in at least one of said cells said subject, and optionally a second composition comprising at least one β2-adrenergic agonist. Pharmaceutical compositions comprising the vector comprising a DNA sequence encoding a β2AR or a mutant thereof, operably linked to a promoter that is functional in at least one of the cells of the subject and kits containing these compositions as well as.. An in vitro method of expressing the β2AR gene in mammalian cells and a method of evaluating the effect of pharmacological compounds on the expression of the β2AR gene is disclosed. |
priorityDate |
2000-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |