| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7aa001f3235c07b0298867908d45e21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_421213e3ab18219141221171e227c42f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_150d891ce3b655b4cdbf8685a0c3a0bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17796a3e929aef7dfde09ca015fe0f94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2ac386b19dd5004e90cebd8cf24df5f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_726f23fe0a7738286c75b839befcf349
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_994d1034e8cc636d2029b05fc7aa2ed2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0306
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-0362
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0276 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate |
2001-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aaafc96952a8dbb7034a20078e185ce9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c97b2ba7ad57466c45f84cad408202fb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a38a9a02bcd3ac948c4029ecee46019e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee9b9d401d951e5d3a902186afc661f6 |
| publicationDate |
2001-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0160152-A2 |
| titleOfInvention |
Transgenic non-human ucp2 knockout mammal |
| abstract |
The present invention provides a transgenic non-human mammal which lacks a functional UCP2 gene. The UCP-2 deficient transgenic knockout mammal described herein provides a source of cells and animals useful to practice methods for the identification and/or evaluation of agents for their ability to affect signaling in cells, such as pancreatic β-cells, in which ATP serves a regulatory function. Further aspects of the invention provide a method for the identification of agents (e.g., therapeutic agents) which inhibit UCP2 activity; a method for the identification of agents which mimic UCP2 activity and a method of treating diseases or conditions associated with UCP2 function (e.g., negative regulation or uncoupling activity). |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11674953-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103947606-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3630086-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103947606-A |
| priorityDate |
2000-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |