http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0159094-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0fc2a22a9271507062ad7e07974d3c58 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63 |
| filingDate | 2001-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fef27f9005a44d027bf7c35ee553c3d |
| publicationDate | 2001-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0159094-A2 |
| titleOfInvention | Method of regulating transcription in a cell by altering remodeling of cromatin |
| abstract | The present invention provides a method of altering remodeling of chromatin in a cell comprising administering to the cell a compound that modulates an interaction of a subunit of a chromatin remodeling complex and a domain within a protein. The compound modulates the interaction by inhibiting or enhancing the subunit of the chromatin remodeling complex and the domain within the protein. The protein may be a transcription factor. The domain may be a nucleic acid binding domain or an activation domain. The nucleic acid binding domain, such as peptide or an artificial zinc-finger domain. The first peptide may be linked to a second protein to form a fusion protein. The nucleic acid may be DNA or RNA. The chromatin remodeling complex may be SWI/SNF, RSC, NURF, CHRAC, ACF, NURD and RSF. The remodeling complex may be tissuespecific. In particular the chromatin remodeling complex may be one of the following SWI/SNF subunits: BRG1, BRM, BAF 155, BAF 170, Inil, BAF 60, BAF 47, or BAF 57. The subunit may be associated with at least one other subunit. The SWI/SNF complex may be E-RC1. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03033701-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7001768-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7785792-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8071370-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0244420-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0244420-A3 |
| priorityDate | 2000-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 742.