| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8679e6625aaacf3f074117a32d588dee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44decf0e9b3189a54c62e6112c6eed09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3a6c6f3210bbefbf94d3878dd3a62da6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-7151
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2878
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate |
2001-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_655e128e7ed89dd29b64053a1d3b3e29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90bb6a24d8b0d36d75093ae3a96ab6d1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c45334a9f135ed652e468d1ed379b688 |
| publicationDate |
2001-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0158953-A2 |
| titleOfInvention |
Identification of a domain in the tumor necrosis factor receptor family that mediates pre-ligand receptor assembly and function |
| abstract |
The present invention provides a polypeptide comprising the isolated amino acid sequence of a pre-ligand assembly domain (PLAD) of a TNF-like receptor. The invention also provides the PLAD for other members of the TNF receptor superfamily. The polypeptides of the present invention can be utilized to inhibit oligomerization of members of the TNF receptor superfamily. These polypeptides can also be utilized to inhibit ligand binding to members of the TNF receptor superfamily. The present invention also provides a composition comprising an inhibitor of TNF receptor oligomerization. Further provided by this invention are members of the TNF receptor superfamily that are lacking a PLAD. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011006914-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2420251-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006059110-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10544229-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8921528-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012172070-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9051392-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9028822-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2420251-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008521426-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007002633-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2371390-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2746290-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007002633-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2011051217-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1814584-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2746291-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010081787-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006038027-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006059110-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010094720-A2 |
| priorityDate |
2000-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |