Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2e62dd5e93362741d284a49e8bd47d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e6ff08fcf59a4f88bfb4a3b26d2e81f |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-162 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
filingDate |
2000-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77c9a631ac5a442f978d689a00cfee5d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f7d8ed7ed007c82464d0455d24beb6f |
publicationDate |
2001-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0151077-A1 |
titleOfInvention |
Methods of regulating il-12 production by administering ccr5 agonists and antagonists |
abstract |
The present invention provides a method for increasing IL-12 production in a cell, comprising administering a CCR5 agonist to the cell. The invention also provides a method for decreasing IL-12 production in a cell, comprising administering a CCR5 antagonist to the cell. Further provided by this invention is a method for treating a disease associated with increased IL-12 production in a subject, comprising administering to the subject a CCR5 antagonist in an amount effective in reducing the disease-associated effect of IL-12, thereby treating the disease associated with increased IL-12 production. Also provided by this invention is a method for increasing IL-12 production in a subject, comprising administering and effective amount of a CCR5 agonist to the subject. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8221988-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AT-412145-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1469849-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004037909-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2003207646-C1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9131722-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1469849-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7943130-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8354431-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113040090-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015174132-A1 |
priorityDate |
2000-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |