http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0146428-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e6829223487b0090452b223e1e58665c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1010e3862914acdd087e73d76911ec6d |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0258 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-245 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-245 |
filingDate | 2000-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_772dfc225f03f2f58cc4c62051433643 |
publicationDate | 2001-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-0146428-A1 |
titleOfInvention | Vaccine strains against infection with pathogenic bacteria |
abstract | Vaccine strains having high safety and potent antigenicity (immunogenicity) and being efficaciously usable as live vaccines against a number of pathogenic bacteria; and live vaccine compositions containing these vaccine strains. The above vaccine strains against infection with pathogenic bacteria comprise pathogenic bacteria with deletion or decrease in the pathogenicity-expressing function which are prepared by transferring, by homologous recombination, a DNA having substitution of mukFEB operon relating to the temperature sensitivity in colony formation by kanamycin tolerance gene into a strain having deletion of DNA adenine methylase gene relating to the pathogenicity-expressing function of pathogenic bacteria (for example, enteropathogenic Escherichia coli, murine typhoid bacillus, abdominal typhoid bacillus, dysentery bacillus, klebsiella, pasteurella and actinobacillus) to achieve double gene mutation. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7026155-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03056008-A1 |
priorityDate | 1999-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.