| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b4bdebe35df7515a3482a1a4d398cf63 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-78
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-06 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-22 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-78 |
| filingDate |
2000-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2885d99bddc09744db1d0859b811e10a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e673cc7746bc21f116312ffa6b2f0ee9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e7db793f948033e9a345a9318cef2c58 |
| publicationDate |
2001-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0144202-A1 |
| titleOfInvention |
Hydantoin intermediates for the synthesis of omapatrilat and methods for producing and using the same |
| abstract |
Omapatrilat (I) is a potent inhibitor of angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP) both in vitro and in vivo and is currently undergoing large scale clinical trials as an anti-hypertensive. Omapatrilat may be synthesized using the S-stereoisomer of compound (V). Compound (V) may be prepared from a novel hydantoin (III). The hydantoin may be prepared from a monoacetal (XI) or via a dinitrile (IV). |
| priorityDate |
1999-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |