| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7150ac269ca8375fc97abc4bcd02beb2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_58ec623cc249d4f1b41da234244e1eb6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f67cbfc14623a6f5eca9853ead954d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b2c3ed17c7b9cc7d0ecce27d0bb56bcb |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C209-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-02 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-08 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-10 |
| filingDate |
2000-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ccb746ac24398b0908b6e3a2b06b6bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc2de6d6d00510a135e1bd495de6eea9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0c282f3de268d6a3691ca965cf5c20e |
| publicationDate |
2001-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0144162-A1 |
| titleOfInvention |
Process for the preparation of secondary and tertiary amines |
| abstract |
N,N-disubstituted amines in which the amino nitrogen atom is bound to the carbon of an aromatic ring disubstituted in the positions ortho to the carbon atom, are prepared by allowing a primary amine and a compound in which an ortho, ortho-disubstituted aromatic compound carrying a nucleofuge substituent, to react in a basic environment in the presence of a catalytic palladium(0) complex and a ligand, the ratio of palladium complex to ligand being greater than at least 1:1. A typical embodiment involves the reaction of 2-methyl-6-ethylphenyl-trifluoromethylsulfonate and (S)-1-methoxy-2-aminopropane in the presence of bis(dibenzylideneacetone)palladium, tri-tert.-butylphosphine, and sodium tert.-butoxide to yield (S)-N-(1-methoxyprop-2-yl)-2-methyl-6-ethylphenylamine. |
| priorityDate |
1999-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |