Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_103281addb3aa9690014f916dde82e53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e1018b924ad1e238642eaad9d2172a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_032faef43d76f9e335df7c0f09e6339f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f0d9e1b4453461b3d78ee19a68903aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49e25bce43c85829dafd8de070decbff |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-203 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-18 |
filingDate |
2000-12-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53af3f7b8a2a59687c9e5cb2889092aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9713217e3d4a2b644e398ba02e8e3b52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4346c093823c30b771794e559c48e125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dffe5bfb1a071fc43f03477fb5cb260 |
publicationDate |
2001-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0142264-A1 |
titleOfInvention |
Method for the synthesis of sialylated oligosaccharide donors |
abstract |
A method for the synthesis of aryl thioglycosides comprising a sialylated residue of β-D-galactose is disclosed. The method consists of preparing by a chemical synthesis a non-sialylated aryl thioglycoside, and enzymatically sialylating the latter with a sialic acid in the presence of a suitable sialyltransferase. The sialylated aryl thioglycoside is then chemically derivatized by standard procedures, to provide a derivative suitable for use as a donor in chemical syntheses of sialylated oligosaccharides. The derivatized sialylated aryl thioglycosides are prepared in high yields, due to reduced number of chemical and purification steps involved in the process. Derivatized aryl thioglycosides useful as building blocks for the synthesis of biologically active sialylated oligosaccharides are also disclosed. |
priorityDate |
1999-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |