| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_916075766043ce900399a4c2eee9f054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f66e931ddfb47f8bb567799223663ee9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_682c9185309a51e0ad6ee085313e0771
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1c7db088945e280359560300d1157b5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee2478b5f813661019eb9cffe779b18f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D279-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D279-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-04 |
| filingDate |
2000-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fecb84ce826820fb8b7356a24f2f32b0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06d02da117f6b6d567afef4a6a2d7707
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9161a782b95d6bda6edf9098fe43b8d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52a0ac26a2e7e6a37e571852e58d2847 |
| publicationDate |
2001-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0136426-B1 |
| titleOfInvention |
Pyridinones to treat and prevent bacterial infections |
| abstract |
Novel pyridinones and their derivatives which are effective in treating or preventing Gram-negative bacterial infections are provided. The pyridinones are stable and easily derivatized; the methods by which these derivatizations occur is described. Two regioselective and functional group tolerant methods for the synthesis of the novel pyridiones are also provided. One such sythetic method involves reacting an imine and a Meldrum's acid derivative in solution. The other synthetic method is a solid phase synthetis of the pyridiones in which an imine is prepared bound to a solid support and a Meldrum's acid derivative is reacted with the imine. Novel imine intermediates useful in the solid phase and solution methods of synthesizing the pyridiones are also described. |
| priorityDate |
1999-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |