Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7eadfb7a35f418febfc06bf2a38467a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_29f910735b06460b1c25ceca2dab478b |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P21-06 |
filingDate |
2000-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9454ff968856f2cdbabffef4356db4a9 |
publicationDate |
2002-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0136419-A9 |
titleOfInvention |
Use of 9-substituted hypoxanthine derivatives to stimulate regeneration of nervous tissue |
abstract |
The present invention comprises a method of stimulating regeneration or survival of a mammalian motor neuron or of a mammalian sensory neuron comprising administering to a mammal an effective amount of a compound that is a 9-substituted hypoxanthine derivative linked through a linker to p-aminobenzoic acid moiety or of a salt or prodrug ester of such a compound. Preferably, the compound is N-4-carboxyphenyl-3-(6-oxohydropurin-9-yl) propanamide. The invention also includes pharmaceutical compositions formulated for stimulation of regeneration of a mammalian motor neuron comprising the 9-substituted hypoxanthine derivative and a pharmaceutically acceptable carrier. |
priorityDate |
1999-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |