http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0136400-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9e6ea8c63e4e310f423e445553dfb3a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fefb0e008cd13742b01e99b978e59482 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c3abccac7bae9414dc8ce09b2d192dc |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C331-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-40 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C331-20 |
| filingDate | 2000-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07dc1a45d4446847cd05bb6a09f935e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce44d4aa7db84f784bcfffd9080195df |
| publicationDate | 2001-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0136400-A1 |
| titleOfInvention | Method for producing 2-chloro-5-chloromethyl-1,3-thiazol |
| abstract | The invention relates to a method for producing 2-chloro-5-chloromethyl-1,3-thiazol from compounds of formula (I), wherein X means Cl, -OR, -SR or NR2, R being H or a suitable protective group; Y means H or Cl and Z means Cl or O, the compounds of formula (I) having at most one double bond between C* and C" or between C" and Z, on the condition that the bond between C" and Z is a double bond when Z is the same as O and a single bond when Z is the same as Cl; with the following intermediate stage: A1) reacting 2,3-dichloropropanal with rhodanide and acetalising to 3-chloro-1,1-dialkoxy-2-isothiocyanato-propane or a2) reacting 2,3-dichloropropanal with thiourea to form a mixture of the hydrochlorides of the compounds N-[[5-(2-aminothiazol)yl]methyl] thiourea and [5-(2-aminothiazol)yl]methylthioformamidine and splitting to obtain the corresponding thiol or amine or b) reacting a compound of formula (I) wherein X means OR, SR or NR2, Y means chlorine and Z means oxygen with thiourea to produce the compound of formula (V), or c) reacting a compound of formula (I), wherein X means OR, SR or NR2, Y means chlorine and Z means oxygen with ammoniumdithiocarbamate or ammoniumthiocarbamate, to produce the compound (VIa) or (VIb); d) converting 1,2,3-trichloropropane to the corresponding thiazolidine and then dehydrogenating or e) converting 1,3-dichloro-prop-1-ene to the corresponding epoxide and then reacting said epoxide with thiourea (e1) or ammoniumdithiocarbamate or ammoniumthiocarbamate (e2). |
| priorityDate | 1999-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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