| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_65f35aac77302d53c6509f6f7bd9805a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f6df56a4e9b17d56d9c57dcf04c46b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f2b1aa309d18149525a633f5d33e01e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_862a2cb716c38d00651ccc9351e414e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f51e77e8842bed94e5b05e2079594cc9 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B15-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C20-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B15-30 |
| filingDate |
2000-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbd861a5823b4dd2dccda8a589a72b6c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d459aad1ab0ee2f311aaf124ffd71724
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a6857ecdb09e7f6cc9d206e79496c21 |
| publicationDate |
2002-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0135316-A9 |
| titleOfInvention |
Computationally derived protein structures in pharmacogenomics |
| abstract |
Provided herein are computer-based methods for generating and using three-dimensional (3-D) structural models of target molecules and databases containing the models. The targets can be protein structural variants derived from genes containing polymorphisms. The models are generated using molecular modeling techniques and are used in structure-based drug design studies for identifying drugs that bind to particular structural variants in structure-based drug design studies, for designing allele-specific drugs and population-specific drugs and for predicting clinical responses in patients. Computer-based methods for predicting drug resistance or sensitivity via computational phenotyping are also provided. Databases containing protein structural variant models are also provided. |
| priorityDate |
1999-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |