| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1abc7ea705ea83007f92881c65f0291f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f4e25d2d3231658e020b1c5207b26bc0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_891d579a5ea1414d9fb100864aa1e2c0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-4718
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-142
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-44 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5091
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-569
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2000-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d65ef85293e64edad66a2ef54a4fb54a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6566cda63de8597a9dc8f3377e0e475a |
| publicationDate |
2001-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0133228-A2 |
| titleOfInvention |
Cancer diagnosis employing cell-sorting and gene-profiles |
| abstract |
Methods for separating living neoplastic cells from dead cells in a tumor sample, using a 'vital stain' (e.g. propidium iodide) are provided. These methods are useful for prognosis, diagnosis, assessment of staging and disease progression in human cancer patients. The first method is a generic method involving antibodies that specifically bind neoplastic cells. The second method is a specific method to test the resistance of neoplastic cells to cytotoxic compounds using antibodies against a discrimination compound for apoptotic cells (e.g. Annexin V). The second method also determines the gene profile after cell sorting using a hybridisation array. The difference in gene expression between drug resistant and drug sensitive tumor cells can thus be employed to make clinical decisions. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11221333-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7635680-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8597899-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1361433-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007139895-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10018631-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007139895-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1361433-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03010337-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8114615-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10962544-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7645739-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7747389-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8655597-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100398663-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7635676-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7635678-B2 |
| priorityDate |
1999-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |