| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63dd5aca32d3fe6e8be7fcc92d199fa8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a546384a5eedf2f5c8026fc8dd0ac6d7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6869
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-715
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2000-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4898f0c5dd36d17bccc0277b19adfca3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f0ba460b329f098c14041d9dd664057 |
| publicationDate |
2001-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0125797-A2 |
| titleOfInvention |
Methods of evaluating whether a test agent is an agent affecting a leptin receptor |
| abstract |
The present invention provides methods of evaluating whether a test agent is an agent affecting the activity of OBR. In said methods, a mammalian cell is cultured and exposed to the test agent. The mammalian cell has a polynucleotide encoding a chimeric receptor subunit comprising an extracellular domain of an OBR subunit, a transmembrane domain of a cytokine receptor subunit and an intracellular domain of a receptor subunit selected from a non-OBR homodimeric cytokine receptor subunit, gp130 and IL-2R β subunit; and has a proliferation dependency on OB. By measuring the proliferation of the mammalian cell, it can be evaluated whether the test agent is an agent which can affect the activity of OBR. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7732133-B2 |
| priorityDate |
1999-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |