http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0118254-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eb571f54c0631b4c22575ff5d56cdfdc http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97eaeeedcc5ee033cbe913c6091b2899 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
| filingDate | 2000-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18d3f8ef2764897d87142e9eae8a9d1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78a7688f052076504bab0088fa3d61a3 |
| publicationDate | 2001-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0118254-A2 |
| titleOfInvention | Mutant of rad51 gene and its use in the diagnosis of predisposition to breast cancer |
| abstract | The present invention describes the identification of a mutant of the RAD51 gene. The mutant is associated with an increase in the risk of developing breast cancer in women who carry a BRCA1 or BRCA2 mutation. The mutant consists of three genetic variants: a guanine to cytosine (G- > C) transversion at nucleotide position 135 in the 5' untranslated region of the RAD51 gene, a guanine to thymine (G- > T) transversion at nucleotide position minus (-) 2339 upstream (5') from the transcription start site of the RAD51 gene, and a deletion of two adenine residues beginning at nucleotide position minus (-) 3189 upstream (5') from the transcription start site of the RAD51 gene. The invention thus provides methods for diagnosing genetic predisposition or susceptibility to breast cancer in a subject. |
| priorityDate | 1999-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.