http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0112655-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_10afea640e3b96a7394c3c166cfa819b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d00e4505c696109ce54e28016d830a65 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate | 2000-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00edf64809fd62df6fbecc3fc2a7458d |
publicationDate | 2001-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-0112655-A1 |
titleOfInvention | Peptides consisting of fragments of gli-1 and sufuh and their use |
abstract | The present invention relates to the field of mammalian signalling pathways, and more precisely to the physical interaction between two components of the Sonic hedgehog (Shh)-Patched (Ptch) signalling pathway, namely GLI-1 and SUFUH. The invention provides peptides consisting of fragments of GLI-1 and SUFUH, respectively which are able to specifically bind to SUFUH and GLI-1, respectively. The invention also provides monoclonal antibodies and antibody fragments specifically binding to these peptides, as well as pharmaceutical compositions containing the peptides, antibodies and/or antibody fragments, said pharmaceutical compositions being useful for treating cancer and diseases influencing cell differentiation and tissue development. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9248128-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004026911-A1 |
priorityDate | 1999-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.