http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0112655-A1

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
filingDate 2000-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00edf64809fd62df6fbecc3fc2a7458d
publicationDate 2001-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0112655-A1
titleOfInvention Peptides consisting of fragments of gli-1 and sufuh and their use
abstract The present invention relates to the field of mammalian signalling pathways, and more precisely to the physical interaction between two components of the Sonic hedgehog (Shh)-Patched (Ptch) signalling pathway, namely GLI-1 and SUFUH. The invention provides peptides consisting of fragments of GLI-1 and SUFUH, respectively which are able to specifically bind to SUFUH and GLI-1, respectively. The invention also provides monoclonal antibodies and antibody fragments specifically binding to these peptides, as well as pharmaceutical compositions containing the peptides, antibodies and/or antibody fragments, said pharmaceutical compositions being useful for treating cancer and diseases influencing cell differentiation and tissue development.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9248128-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004026911-A1
priorityDate 1999-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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