| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_880d19c6ddd832120f96b9d521b6e791
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_093e2aebdbef534bdc4982fecbdd0beb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75ca0b24919e428ea83e8ac78f5c95c2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2d6eb785a13032f52d1f7f654acac96d |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate |
2000-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d79a0f0290b518a2716b371acafa7ae
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b7273afcd4ac5a3a18b191b1c5eddf8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_862b3c6a7e4336db1c13d559521fda49 |
| publicationDate |
2001-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0110378-A2 |
| titleOfInvention |
Controlled release from copolymers of acrylic or methacrylic acid/l-dopa, acrylic or methacrylic acid/l-$g(a)-methyl dopa, acrylic or methacrylic acid/carbidopa and their combinations |
| abstract |
The invention relates to site directed drug delivery systems providing a controlled release of L-dopa, carbidopa or L-alpha-methyldopa and/or their combinations which eliminates or at least reduces the deleterious side effects of these drugs. Biologically active copolymers having directional characteristics to the digestive mucous tissue comprise L-dopa, carbidopa or L-alpha-methyldopa chemically combined with biologically acceptable poly(acrylic acid) or poly(methacrylic acid). The copolymers are obtained by a process comprising the steps of: (a) reacting L-dopa, carbidopa or L-alpha-methyldopa with a chlorination agent; (b) bringing into reaction the product of step (a) and poly(acrylic acid) or poly(methacrylic acid) in the presence of a suitable catalyst; (c) washing the copolymer obtained in step (b) with a suitable organic solvent and drying it until constant weight. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006039022-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005056708-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006039022-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8491929-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007517776-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006026556-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006026556-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011086095-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005056708-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006026504-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006026504-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007002318-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007002318-A3 |
| priorityDate |
1999-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |