Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f2ae64e05caa86011c606e138971cb8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-11 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-2408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate |
2000-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_85057189012c23ad79276abda1fa640d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0204866ed1faa6ac864a481556f307c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f05a43c445ec1840770f8946e209afb2 |
publicationDate |
2001-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0109385-A2 |
titleOfInvention |
Attachment of oligonucleotides to solid supports through schiff base type linkages for capture and detection of nucleic acids |
abstract |
Derivatized oligonucleotides (ODNs) are coupled to a solid support in improved yield resulting in a high density of coupled oligonucleotide per surface unit of the support, through a Schiff base type bond formed between an NH2 group attached either to the solid support or to the ODN and an aromatic aldehyde attached to the other of the solid support and the ODN. The preferred solid support-ODN conjugate is formed between semicarbazide groups attached to a glasss surface and an aromatic aldehyde attached at either 3', or 5' end of an ODN or to an intermediate nucleotide of the ODN. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7186813-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0214558-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0214558-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7102024-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02097442-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/FR-2825095-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7173125-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7999098-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7732628-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7462689-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6800728-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7129229-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0170685-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE46171-E |
priorityDate |
1999-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |