http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0109375-A2
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69df0c0b3d3d93288e5c810e2eb6797e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7d3effb4e33b7ef461014fc9745df56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0474773d83c106abaa80a59579a74b99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ed2085748d0da898ca204d006a8174a9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2000-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_caa5a4144a7924e76ba58c8fcff677ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0c7cdb4af6aca3f71b67108c6d2d812 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd10c7e9a3dc4e2acc87fa3bdb50ab01 |
| publicationDate | 2001-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0109375-A2 |
| titleOfInvention | Inducible screen for drug discovery |
| abstract | A method for identifying a polynucleotide, the expression of which is modulated in the presence of nitric oxide (NO), which method comprises: (i) providing an mRNA or cDNA population from cells which contain a polynucleotide construct, which construct comprises: (a) a promoter operably linked to a coding sequence, wherein the promoter is responsive to ecdysone or an analog thereof and the coding sequence encodes a nitric oxide synthase (NOS) or a functional variant thereof; or (b) a promoter operably linked to one or more tetracycline operator site sequences and a coding sequence in that order, wherein the coding sequence encodes a nitric oxide synthase (NOS) or a functional variant thereof; (ii) providing an mRNA or cDNA population from cells as defined in step (i), said cells having been contacted with ecdysone or an analog thereof; and (iii) comparing the populations of steps (i) and (ii), thereby to determine which polynucleotides show modulated expression in the presence of NO. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004017950-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004017950-A3 |
| priorityDate | 1999-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 672.