Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8e4d0101c364ff3e7df89be5b20ab4b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2658d45a8e9c71b9598e2bf83242bab3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f618f5f7f463a0bd50d555bb314067c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6853 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-34 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66 |
filingDate |
2000-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5248d98633d24a4c8709443a8427a520 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b453c0e64f7c9e55643bf55f1b5c695 |
publicationDate |
2001-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0106017-A2 |
titleOfInvention |
Methods for preparing quantities of preselected polynucleotide sequences and uses thereof |
abstract |
Methods are described for the preparation of quantities of preselected polynucleotide sequences in purified form. The method is independent of length or sequence, and can be used to prepare multi-milligram quantities of, for example, single length, isotope-enriched duplex DNA following a single-step chromatographic purification of the desired product. The method of the present invention allows for preparative scale synthesis of DNA yielding a single product length. The application of the method to NMR spectroscopy of DNA provides the opportunity to identify biologically relevant interactions between polynucleotide sequences and other macromolecules, and assist in the identification and development of agents having therapeutic utility as a consequence of the promotion or antagonism of these interactions. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9944966-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2774996-A1 |
priorityDate |
1999-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |