| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b798ab0c6eb328544c916dba351fd8f9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_20e544a162a9c56024fec7e0d9e58329
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ca32fd2a44fd326ffd027a75a57bd13f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_960bcda6702b2939237639ce1f885de5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5bb9364fdde200ddee74491e152e3649 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-203
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-132
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-198
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate |
2000-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bc6fca2a239174a40fcb4683773549e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2af9dc987f8e57b6bf186473f035589
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3cb58622f9d3e8f9a067ba737133defe |
| publicationDate |
2001-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0104349-A2 |
| titleOfInvention |
Method for the diagnosis or the prognosis of alzheimer disease therapeutical composition for preventing or treating alzheimer disease |
| abstract |
The invention relates to a method of predicting an increased risk of a patient having Alzheimer's disease (AD) or for a subject of developing AD comprising: a) assaying a DNA-containing biological sample for the allele of the APOE gene; b) assaying the plasmatic level of protein Lp(a) or glycoprotein Apo(a), wherein the presence of an ε4 allele of the APOE gene and an increased plasmatic level of [Lp(a)]/Apo(a) indicates an increased risk for the patient having Alzheimer's disease or developing AD. The invention further provides a therapy for preventing or treating AD consisting of decreasing the plasmatic level of Lp(a) or the interaction of Lp(a) with its receptor in a patient bearing at least one APOE ε4 allele. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2446887-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9351979-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007092380-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8586568-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007092380-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10058562-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8227457-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8722651-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9987292-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9233113-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2289511-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8062842-B2 |
| priorityDate |
1999-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |