abstract |
The present invention relates to an exothermic device (500) for topically delivering an active agent comprising a liquid reservoir (220) comprising water, a heating element (210) comprising an oxidizable material, an oxygen-permeable outer-layer (250), an active agent, and a water-impermeable layer (130), wherein upon the rupturing of the liquid reservoir, the water contacts the heating element and the oxygen to create an exothermic reaction. |