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publicationDate 2001-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0102422-A9
titleOfInvention PROCESS FOR OBTAINING 17β-(N-TERC-BUTYLCARBAMOYL)-3-ONE-4-AZA-STEROIDS
abstract 17β-(N-terc-butylcarbamoyl)-3-one-4-aza-steroids (I) can be obtained by a process which comprises the reaction of 17β-(alcoxycarbonyl)-3-one-4-aza-steroid with terc-butylamide of lithium in an organic solvent. Some compounds of formula (I), for example finasteride, are useful as inhibitors of 5-α-reductase and can be used in the treatment of benign prostatic hyperplasia and alopecia.
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