| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_767c55ecaa020d40b6289e97c170039a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3b4761b633aa2644a63dee03bd4f6d64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6d70bbba2b5199b34b304cb882733d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_93d0064b935e8bdee92779a777e49a40 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D307-87 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D307-87 |
| filingDate |
2000-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_688f8d234ab7c244adaf4273bc74e27c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74b7802e216c20578deb5113e4f21f76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3b25eef7fbac35cdfd521cb8c1735f8 |
| publicationDate |
2001-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0102383-A2 |
| titleOfInvention |
Process for the synthesis of citalopram |
| abstract |
A new process is described for the synthesis of citalopram characterized by the conversion of 1-(4'-fluorophenyl)1-3-(dimethylaminopropyl)-5-halophthalane in the corresponding Grignard reagent; this intermediate product may be converted into citalopram via intermediate formation of an aldehyde and in the subsequent transformation of the functional group via oxime or hydrazone; or else be converted into citalopram via reaction with compounds containing a cyano group bound to a leaving group. The process described makes it possible to obtain citalopram in high yields, and does not involve the use of drastic conditions of temperature. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2360150-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111533662-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111533662-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7030252-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004014821-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022152078-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7148364-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7582780-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6753433-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8067640-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1281707-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2141156-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6768011-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6849749-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03011846-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0204435-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03011846-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10112829-C1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-1298713-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102503759-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6579993-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6660873-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7002025-B2 |
| priorityDate |
1999-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |