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filingDate 2000-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67b483cb31959fe230252c806253ba27
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publicationDate 2001-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0100678-A1
titleOfInvention Human monoclonal antibodies to hiv-1 envelope glycoprotein gp120
abstract This invention relates to 21 monoclonal antibodies to HIV-1 gp120 which were isolated from three Fab libraries prepared from RNA isolated from the lymph node of a type 1 human immunodeficiency virus (HIV-1) seropositive individual. Of the 21 antibodies, seven recognize the CD4 binding site of gp120, eight recognize the V3 loop and six recognize an as yet unidentified epitope of gp120. This invention further relates to diagnostic methods which utilize the antibodies and to pharmaceutical compositions which employ these antibodies therapeutically and prophylactically.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1498426-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10280219-B2
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priorityDate 1999-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 30.