Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2c7b31f7eba80c493c49e5ddfcee7d8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_764af232db22c9b8459ec135e3b2ba6e |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1063 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-10 |
filingDate |
2000-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67b483cb31959fe230252c806253ba27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7df88ed85813336cd64ac5d09b50a58c |
publicationDate |
2001-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0100678-A1 |
titleOfInvention |
Human monoclonal antibodies to hiv-1 envelope glycoprotein gp120 |
abstract |
This invention relates to 21 monoclonal antibodies to HIV-1 gp120 which were isolated from three Fab libraries prepared from RNA isolated from the lymph node of a type 1 human immunodeficiency virus (HIV-1) seropositive individual. Of the 21 antibodies, seven recognize the CD4 binding site of gp120, eight recognize the V3 loop and six recognize an as yet unidentified epitope of gp120. This invention further relates to diagnostic methods which utilize the antibodies and to pharmaceutical compositions which employ these antibodies therapeutically and prophylactically. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1498426-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10280219-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9718883-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10311248-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7604799-B2 |
priorityDate |
1999-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |