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filingDate 2000-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b7f282710c8c94170e260510af72b75
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publicationDate 2001-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0100570-A1
titleOfInvention Intermediates for the synthesis of benzimidazole compounds and process for the preparation thereof
abstract Problem: To provide intermediates for the synthesis of benzimidazole compounds having an excellent antihyperglycemic activity or salts thereof and a process for the preparation thereof. Means for solutions: A process for the preparation of benzimidazole compounds (I), characterized by condensing an amine derivative (III) with a carboxylic acid derivative (II) to form a compound (IV) and subjecting the compound (IV) to ring closure in the presence of an acid (wherein R1 is C1-C6alkyl, C1-C6alkoxy, or the like; R2 is C1-C6alkyl; and R3 is hydrogen or a protective group).
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