| abstract |
The invention relates to a stable radioactive nanoparticle and to a method for the production thereof, whereby a nanoparticle is reacted with a radioactively marked molecule, especially in an aqueous medium, and covalent binding or the radioactively marked molecule to the nanoparticle is effected. The nanoparticle normally has a size ranging from 10 to 1000 nm. Other molecules selected from the following groups can be covalently bound to the nanoparticle: antigens, antibodies, nucleic acids or proteins, enzymes, medicaments or receptor ligands. The radioactive nanoparticles according to the invention are particularly suitable for medical and diagnostic purposes, such as markers for cellular antigens, the study of phagocytotic processes, as microinjectable cell marker, for scintigraphy, aerosol characterization, pulmonary absorption, mucocillary transport assessments, blood tests or tumor treatment and diagnosis and for agglutination assays and/or assays by quantification of an immobilization of nanoparticles. |