| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_092b1f7339fec8139ee9524782622a6c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00459
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-0059
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00585
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0487
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00454
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00418
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00319
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0877
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0867
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0864
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0829
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0816
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B60-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00351
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00317
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00315
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00725
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-0072 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C201-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J19-0046
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-047 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B50-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B60-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-60 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C205-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01L3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-50 |
| filingDate |
2000-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71ebc7f86473d0b71bfe434720f81089
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e344b46404e0eed86bdcef968e56b5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7aef72d1b74c66d0d839723c9a2ad213 |
| publicationDate |
2000-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0076662-A2 |
| titleOfInvention |
Microenabled chemical reaction in microfluidic chips |
| abstract |
A chemical process to obtain products of higher purity or in shorter time is provided by performing chemical reactions in a reactions volume less than 1 microliter. The advantages of this process are due to better mixing or heat exchanche (each 10 fold decrease in reaction volume leads to a 100-fold improvement mixing or heat exchange) or better surface to volume ratio. Better surface to volume ratio is a major factor in reactions critically dependent on surface mediated events such as heterogeneous catalysis. This increase in yield and speed of reaction can be conducted in parallel sets of reaction chambers provided by multilayer glass and silicon chips. Reagents can be added via a microfluidic chip incorporating channels and orthogonal row/column reagent delivery options. This discovery is amendable to solid supported synthesis as well as solution synthesis. Because of the better surface to volume ratio, this process is particularly useful with solid catalyst on the edges of the reaction chamber and can be used for hydrogenation, and hydroformulation. This process is demonstrated in reactions involving nucleophilic aromatic substitution on a solid support. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7001740-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7178386-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7351575-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111085281-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7371563-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6594432-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6953551-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6803205-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7439056-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7074327-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6967074-B2 |
| priorityDate |
1999-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |