http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0075661-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_390be8b40737dd62f57f366e17a9af5d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2510-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-9406 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94 |
| filingDate | 2000-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a8765d14e1f6bacad402bdc4c3c5dff http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74f6a85706d9b45244d31e21a5cb9dec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91d4af949f9558632357efd981dfb810 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f30369c63c4859a6e745f52eefcd65c |
| publicationDate | 2000-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0075661-A1 |
| titleOfInvention | Method for identifying compounds which affect synaptogenesis |
| abstract | A method is provided for identifying a compound which affect the formation of AMPA receptors into aggregates. A method is also provided for identifying a compound which affects the formation of synaptic connections. A method is provided for identifying a compound that modulates immediate early gene expression. A method is further provided for increasing the number of excitory synapses of a neuron, including introducing into the neuron a polynucleotide sequence encoding a Narp operatively linked to a promoter, or a Narp polypeptide, thereby increasing the number of excitory synapses of the neuron. A method is provided for treating a subject with a disorder associated with a decrease in a function or expression of Narp, including administering to the subject a therapeutically effective amount of a compound that augments Narp function or expression. A method is provided for treating a subject with a disorder associated with an increase in a function or expression of Narp, including administering to the subject a therapeutically effective of a compound that inhibits Narp function or expression. A method is provided for treating a patient having or at risk of having a disorder associated with decreased Narp expression. The method includes introducing into a cell of a patient having a disorder associated with decreased Narp expression or function a polynucleotide sequence encoding a Narp polypeptide operatively linked to a promoter. A method is provided for treating a subject having a deficiency in a neuron's immediate early gene responsiveness to a stimulus. The method includes administering a nucleic acid encoding a Narp polypeptide to said subject, wherein the administration results in amelioration of the deficiency. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7736654-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7202211-B2 |
| priorityDate | 1999-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.