| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c646f75c4f7c6349f35c8fe01934921 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2202-22 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0058
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0035
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0294
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0226
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0215 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L2-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02 |
| filingDate |
2000-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_582be18ee85b424a3dfdeeafd1ca7ba7 |
| publicationDate |
2000-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0074483-A1 |
| titleOfInvention |
Improved storage and maintenance of blood products including red blood cells and platelets |
| abstract |
Cell membrane maintenance of red blood cells and platelet concentrates is improved by the addition of 1 mM - 10 mM L-carnitine and derivatives. This improvement allows extension of the period of viability of packed red blood cells and platelet concentrations beyond current periods. Additionally, the materials so treated exhibit extended circulation half life upon transfusion to a patient. Improvements in membrane maintenance achieved by this method permit irradiation of sealed containers of blood products so as to substantially sterilize and destroy leukocytes in the same. The addition of L-carnitine and derivatives also suppresses bacterial growth and reduces glycolysis in whole blood and blood fractions. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005524714-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10385317-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10612000-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9394518-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8512942-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8968993-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9982230-B2 |
| priorityDate |
1999-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |