abstract |
A method and a composition for preventing or reducing the incidence of post surgical adhesion formation is disclosed. The method involves application of fibrin monomer composition under polymerizing conditions to the surgical wound site. The fibrin monomer composition free of exogenous thrombin, free from proteins, enzymes or polymers foreign to the patient polymerize at the surgical wound site to form the fibrin polymer that provides hemostasis and promotes wound healing while functioning as a barrier/sealant. Autologous plasma proteins derived from the patient's blood may be added to the sealant composition before or during application to the surgical wound site. |