http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0072017-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_05de1467384e541d6f4106f4be0d6016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_452a67dc7a2e797d5b8136c7447f4458 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac9442e962452275a63c777abad46223 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba88628c38067ef159833f475942f6bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b68686fb3f724480714ec03f5994b1b4 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-5754 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74 |
filingDate | 2000-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d6bfe3fe0ba3194141062788317a51c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cdf0cb5af1f38d62b1379e42459d96c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6142d38be6d1a45a7df256dffa7001d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ca900fd51b6f4c165f41498dc5311be |
publicationDate | 2000-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-0072017-A1 |
titleOfInvention | Diagnosis of conditions associated with activation of endothelin |
abstract | This invention relates to the diagnosis of conditions associated with activation of the endothelin system in a patient, to the assessment of disease severity, and to the detection or identification of patients who are at risk of developing cardiovascular disease. In addition, the invention is applicable to the monitoring of the effectiveness of therapy for such conditions. The invention is particularly, but not exclusively, directed to diagnosis, assessment of disease severity, monitoring the effectiveness of therapy, and detection of the risk of development of cardiovascular diseases, such as chronic heart failure or hypertension, and to identifying agents which are useful in the treatment of cardiovascular diseases. According to a first aspect, the invention provides a method of diagnosis of a condition associated with activation of endothelin in a patient, which method comprises the steps of: (i) determining the level of endothelin (ET) in a sample of saliva from the patient, and (ii) comparing the ET level so determined with a pre-determined standard; wherein an elevated level of ET in the saliva sample from the patient is indicative of said condition in the patient. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2267456-A3 |
priorityDate | 1999-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.