Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_02141b3c40fccc362747df3bd720a2c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e83d93ed02bbd6159e99b5a7796e3686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0221cfbb710aca0e7f791b87705949d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc197a31fb34069c7e1a94c407dbaf93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e544ed9d5b45202f7faffd92e16f711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_029b7a1bd54456a72b9db741f0a4996b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_709f004185fd7ee40fdbe33c42196e7c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-78 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-80 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-82 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 |
filingDate |
2000-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfc2075933b4cb9112764dbdf93c0795 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2f4611012a134ba3fa4ab9ff67dc50a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29e38bf704d12d20fac04bcc847107e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_718978a2dbd4c43fa51667203673fd52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc171b67e0bb62d7d25d97824b403984 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19a5fb1efbd2c1ca747c051eaf84109f |
publicationDate |
2000-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0071579-A2 |
titleOfInvention |
Regulating organelle homeostasis in a cell factory |
abstract |
The present invention relates to a method for modulating the production of secondary metabolites in the fungus Penicillium chrysogenum by influencing the homeostasis of organelles by modulating a least one gene which is directly related to organelle homeostasis in this fungus. Preferably, the organelle homeostasis is modulated by genetically engineering at least one gene encoding a protein which is responsible for organelle biogenesis (the expression and/or activity of which is to be increased) and/or at least one gene encoding a protein which is responsible for organelle degeneration (the expression and/or activity of which is to be decreased). Genes involved in organelle biosynthesis in P. chrysogenum are exemplified by the so-called pex11 gene. Genes involved in organelle degradation are exemplified by the so-called vps15 and pdd1 genes. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014003555-A1 |
priorityDate |
1999-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |