| abstract |
A matrix comprising: a) a polymeric base matrix comprising macropores (pore system 1) and b) an interior material, possibly porous (pore system 2), retained within the macropores. The matrix is characterized in that there is a continuous free volume between the interior material and the pore walls of the macropores. A method for manufacturing a matrix comprising a base matrix having macropores in which an interior material is located. The method is characterized in comprising the steps: (i) providing a base matrix having macropores; (ii) filling the macropores with a soluble form of the interior material; (iii) transforming the insoluble form to an insoluble form; (iv) shrinking the insoluble form; and (v) irreversibly stabilising the material in its shrinked form. The matrix can be used in separation methods, cell culturing, solid phase synthesis of organic molecules, and in catalytic reactions (such as enzyme reactions) and other uses in which porous support matrices are used. |