| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc0df9b2de95bdafb3a28a5a42a7770f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1234
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-586
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1812
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1217 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B5-055
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61B8-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01R33-28 |
| filingDate |
1999-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7436ab0bf5601c467e0aeee57fb82460
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7d1a4fb35c0dbfaee2f0cd66db6977a |
| publicationDate |
2000-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0071172-A1 |
| titleOfInvention |
Site specific binding system, nuclear imaging compositions and methods |
| abstract |
A method for ligand-based binding of lipid encapsulated particles to molecular epitopes on a surface in vivo or in vitro comprises sequentially administering (a) a site-specific ligand activated with a biotin activating agent; (b) an avidin activating agent; and (c) lipid encapsulated particles activated with a biotin activating agent, whereby the ligand is conjugated to the particles through an avidin-biotin interaction and the resulting conjugate is bound to the molecular epitopes on such surface. The conjugate is effective for imaging by x-ray, ultrasound, magnetic resonance, positron emission tomography or nuclear imaging. Compositions for use in ultrasonic imaging of nature or synthetic surfaces and for enhancing the acoustic reflectivity thereof are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11185600-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2708244-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014041150-A1 |
| priorityDate |
1997-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |