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filingDate 2000-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2000-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0066779-A1
titleOfInvention Comparative fluorescence hybridization to oligonucleotide microarrays
abstract The present invention provides methods of determining relative copy number of target nucleic acid sequences and precise mapping of chromosomal abnormalities associated with disease. The methods of the invention use target nucleic acid sequences immobilized on a solid surface, to which a sample comprising two sets of differentially labeled nucleic acid sequences are hybridized. The hybridization of the labeled nucleic acid sequences to the solid surface is then detected using standard techniques.
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