| abstract |
The patent application describes a method for the enzymatic, chiral synthesis of L-phosphinothricine by means of transamination from a corresponding keto acid PPO with aspartate as aminodonor. Quantitative conversion can be obtained by means of suitable reaction engineering using approximately equimolar amounts of aminodonor and aminoacceptor, whereby the donoramino acid aspartate is completely used. The use of thermostable transaminases enables high reaction velocity and correspondingly high room/time efficiencies. |