http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0064466-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e96496a9949403e2af2ca913e65bfec |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-104 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-095 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 |
| filingDate | 2000-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55114769e6b34013e09ceec271b90cfa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f5a11de2c9555d23cd3e3a75882ab82 |
| publicationDate | 2000-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0064466-A1 |
| titleOfInvention | Localization of major peptide autoepitopes for nucleosome specific t cells of systemic lupus erythematosus |
| abstract | The present invention includes peptides derived from nucleosomal histone proteins which are useful for delaying the onset and progression of systemic lupus erythematosus (i.e. lupus or SLE). The peptides of the invention span the histone proteins (i.e. H1, H2A, H2B, H3, and H4). The invention additionally encompasses isolated nucleic acids which encode these histone peptides as well as pharmaceutical compositions which comprise one or more of a histone peptide. Further, the invention provides kits which comprise one or more histone peptides or isolated nucleic acids encoding histone peptides and an instructional material. The invention also provides methods of using these compositions and analogs of histone peptides to inhibit an immune response and associated inflammation in an animal and to treat disorders in an animal which are related to the production of autoantibodies and complications thereof, such as inflammatory diseases, autoimmune disorders, and nephritis. In addition, the invention includes methods for developing diagnostic and prognostic reagents using the histone peptides and isolated nucleic acids encoding the instone peptides, for the purpose of tracking autoimmune T helper cells and B cells of SLE are also included. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006064481-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1672080-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1572069-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1572069-A4 |
| priorityDate | 1999-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 301.