abstract |
A method for treatment of a disease or condition associated with increased numbers of neutrophils and/or neutrophil over-activation in a mammal such as a human, which method comprises administering an effective, non-toxic and pharmaceutically acceptable amount of a PPARĪ· agonist, such as fosiglitazone (BRL49653) or its maleate salts, or pioglitazone, to a mammal in need thereof. |