abstract |
Methods of detecting and/or diagnosing intimin-expressing microorrganisms such as enteropathogenic Escherichia coli (EPEC), enterohemorrhagic E.coli, C. rodentium and/or RDEC-1, as well as kits for use in such methods are provided. In particular, methods based antisera raised against conserved regions are described, as well as polypeptide regions useful in the production of antisera. Vaccines based on such peptides are also described herein. In addition, methods of typing/classification of such bacteria are also described herein. Finally, methods for the isolation of intimin-expressing microorganisms are also provided. |