| abstract |
A method for preparing through azides tricyclic amino alcohol derivatives useful in the treatment and prevention of diabetes, obesity, hyperlipidemia and so on and represented by general formula (1): [wherein R1 is lower alkyl or benzyl; *1 represents an asymmetric carbon atom; R2 is hydrogen, halogeno or hydroxyl; and A is a substituent represented by general formula (a) or (b): (wherein X is NH, O, or S; R5 is hydrogen, hydroxyl, amino, or acetylamino; and *2 represents an asymmetric carbon atom when R5 is not hydrogen)], which makes it possible to prepare the derivatives by a short, easy, inexpensive and practical production process excellent in industrial workability. |