| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8649e3ccbc8f366f515a303a235d501b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c35234fb7a03cee7ba76fc2585b0bc4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e665ebe0cee8762bc2eb4aad22a14a49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d83da861f073bf3c8b44e5ae9c666164
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eccd894c99fea2d1c0c8735872bb2309
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5a26ffe6233d9f5f240321d13d0bf5b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_346e92d4135bd207670693b9df20c1bb |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43536
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-435 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-616
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-727
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-00 |
| filingDate |
2000-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d28dabbbfb0a385d2d56599fa7ea1f83
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_561a66f7ed0fa690f83d074e5359e12d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cebd4d01bec4d5e54c42ccab540b87ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b7ec2cbd4015f5e39fe39e63c71bf51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_902f80abeebf2d3786de135f2f876777
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53b81ad15a27042eca87a049d5a9569e |
| publicationDate |
2000-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0056885-A1 |
| titleOfInvention |
Protein for blocking platelet adhesion |
| abstract |
A naturally occurring protein isolated from the saliva of the medicinal leech Hirudo medicinalis is described which strongly binds to collagen thus acting as an inhibitor of natural platelet adhesion to collagen. The protein has a molecular weight of about 12 000, an acidic isoelectric point and contains six cysteins. The protein was sequenced and the gene was cloned from a H. medicinalis cDNA-library. Procedures for producing such polypeptide by recombinant techniques are disclosed. The recombinant and the natural occurring proteins are potent inhibitors of collagen-dependent platelet adhesion and therefore useful for the therapeutic treatment of various conditions related to hard disease and diseases of the circulation system. Furthermore the protein is useful for coating natural or artificial collagen surfaces in order to render them nonadhesive for cells and prevent the activation of cells. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7507412-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10772906-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-202012012998-U1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7053051-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0215919-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6881722-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110945020-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110945020-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8188034-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11021710-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7919465-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7691839-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7459438-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7090986-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0215919-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008006189-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004506690-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11376273-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2001295506-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100794277-B1 |
| priorityDate |
1999-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |